Article
Impact of gene polymorphisms on clinical outcome for stage IV melanoma patients treated with biochemotherapy: an exploratory study.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Feb 2005
Liu Dongxin, O'Day Steven J, Yang Dongyun, Boasberg Peter, Milford Robert, Kristedja Tim, Groshen Susan, Weber Jeffrey
Abstract excerpt
PURPOSE: Biochemotherapy can achieve high response rates in advanced melanoma, but the factors that influence regression and survival remain unknown. The present exploratory study tested the hypothesis that cytokine gene polymorphisms predict clinical outcome in stage IV melanoma patients treated with biochemotherapy. EXPERIMENTAL DESIGN: Ninety patients with stage IV melanoma were treated with biochemotherapy,...
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