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Article

Mechanisms of fluoroquinolone monoresistance in Mycobacterium tuberculosis.

FEMS microbiology letters - 1 Apr 2014

Lu Jie, Liu Min, Wang Yufeng, Pang Yu, Zhao Zhuo

Abstract excerpt

The gyrase mutations and efflux pumps confer fluoroquinolones (FQ) resistance in Mycobacterium tuberculosis. However, the contribution of two mechanisms in FQ mono-resistant M. tuberculosis is still unclear. Here, we investigated the contribution of gyrase mutations and efflux pumps to FQ resistance among 17 clinical FQ mono-resistant strains. Our data showed that gyrase mutations in gyrA QRDR were only...

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PMID: 24822277
DOI: 10.1111/1574-6968.12401

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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