Article
A heuristic algorithm for haplotype reconstruction from aligned weighted SNP fragments.
International journal of bioinformatics research and applications - 1 Jan 2013
Wu Jingli, Wang Jianxin, Chen Jian'er
Abstract excerpt
Haplotyping problem has been the subject of extensive research in recent years, and is one of the hottest areas of Computational Biology today. In this paper, we study the single individual Single Nucleotide Polymorphism (SNP) haplotype reconstruction problem. A heuristic algorithm is proposed for assembling a pair of haplotypes from a set of aligned weighted SNP fragments. Computational experiments indicate that...
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