Article
Using genetic algorithm in reconstructing single individual haplotype with minimum error correction.
Journal of biomedical informatics - 1 Oct 2012
Wang Tai-Chun, Taheri Javid, Zomaya Albert Y
Abstract excerpt
Discovering ways to reconstruct reliable Single Individual Haplotypes (SIHs) becomes one of the core issues in the whole-genome research nowadays as previous research showed that haplotypes contain more information than individual Singular Nucleotide Polymorphisms (SNPs). Although with advances in high-throughput sequencing technologies obtaining sequence information is becoming easier in today's laboratories,...
Topics
- Algorithms
- Genetic Testing
- Genomics
- Haplotypes
- Humans
- Models, Genetic
- Polymorphism, Single Nucleotide
- Sequence Analysis, DNA
