Article
Haplotype assembly from aligned weighted SNP fragments.
Computational biology and chemistry - 1 Aug 2005
Zhao Yu-Ying, Wu Ling-Yun, Zhang Ji-Hong, Wang Rui-Sheng, Zhang Xiang-Sun
Abstract excerpt
Given an assembled genome of a diploid organism the haplotype assembly problem can be formulated as retrieval of a pair of haplotypes from a set of aligned weighted SNP fragments. Known computational formulations (models) of this problem are minimum letter flips (MLF) and the weighted minimum letter flips (WMLF; Greenberg et al. (INFORMS J. Comput. 2004, 14, 211-213)). In this paper we show that the general WMLF...
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