Article
SpeedHap: an accurate heuristic for the single individual SNP haplotyping problem with many gaps, high reading error rate and low coverage.
IEEE/ACM transactions on computational biology and bioinformatics - 1 Jan 2000
Genovese Loredana M, Geraci Filippo, Pellegrini Marco
Abstract excerpt
Single nucleotide polymorphism (SNP) is the most frequent form of DNA variation. The set of SNP's present in a chromosome (called the haplotype) is of interest in a wide area of applications in molecular biology and biomedicine, including diagnostic and medical therapy. In this paper we propose a...
Topics
- Algorithms
- Base Sequence
- Chromosome Mapping
- DNA Mutational Analysis
- Haplotypes
- Humans
- Molecular Sequence Data
- Polymorphism, Single Nucleotide
- Reproducibility of Results
- Sensitivity and Specificity
- Sequence Analysis, DNA
- Software