Article
SpeedHap: an accurate heuristic for the single individual SNP haplotyping problem with many gaps, high reading error rate and low coverage.
IEEE/ACM transactions on computational biology and bioinformatics - 1 Jan 2000
Genovese Loredana M, Geraci Filippo, Pellegrini Marco
Abstract excerpt
Single nucleotide polymorphism (SNP) is the most frequent form of DNA variation. The set of SNP's present in a chromosome (called the haplotype) is of interest in a wide area of applications in molecular biology and biomedicine, including diagnostic and medical therapy. In this paper we propose a new heuristic method for the problem of haplotype reconstruction for (portions of) a pair of homologous human...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
