A comparison of several algorithms for the single individual SNP haplotyping reconstruction problem.

Abstract excerpt

MOTIVATION: Single nucleotide polymorphisms are the most common form of variation in human DNA, and are involved in many research fields, from molecular biology to medical therapy. The technological opportunity to deal with long DNA sequences using shotgun sequencing has raised the problem of fragment recombination. In this regard, Single Individual Haplotyping (SIH) problem has received considerable attention...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Algorithms
• Share to Base Sequence
• Share to Haplotypes