Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Expression and Prognostic Significance of Human Epidermal Growth Factor Receptors 1 and 3 in Gastric and Esophageal Adenocarcinoma.

PloS one - 1 Jan 2016

Hedner Charlotta, Borg David, Nodin Björn, Karnevi Emelie, Jirström Karin, Eberhard Jakob

Abstract excerpt

BACKGROUND: Gastric and esophageal adenocarcinomas are major global cancer burdens. These cancer forms are characterized by a poor prognosis and a modest response to chemo- radio- and targeted treatment. Hence there is an obvious need for further enhanced diagnostic and treatment strategies. The aim of this study was to examine the expression and prognostic impact of human epidermal growth factor receptor 1...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma
Share to Esophageal Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Kaplan-Meier Estimate

Share to Lymph Nodes

Share to Neoplasm Metastasis

Share to Proportional Hazards Models

Share to Receptor, ErbB-3

Share to Stomach Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 26844548
DOI: 10.1371/journal.pone.0148101
PMCID: PMC4742525

Genes

EGFR
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Expression and Prognostic Significance of Human Epidermal Growth Factor Receptors 1 and 3 in Gastric and Esophageal Adenocarcinoma.PMID 26844548Read ↗

Protein expression of HER2, 3, 4 in gastric cancer: correlation with clinical features and survivalSemantic proximity Read ↗

Prognostic Implications of Altered Human Epidermal Growth Factor Receptors (HERs) in Gastric Carcinomas: HER2 and HER3 Are Predictors of Poor OutcomeSemantic proximity Read ↗

Alterations in epidermal growth factor receptors 1 and 2 in esophageal squamous cell carcinomas.Semantic proximity Read ↗

EGFR gene amplification is relatively common and associates with outcome in intestinal adenocarcinoma of the stomach, gastro-oesophageal junction and distal oesophagusSemantic proximity Read ↗

Epidermal growth factor receptor expression in gastric tumors and its relationship with the germline polymorphisms - 216 G>T, -191 C>A, (CA) n IVS1, and R521K.Semantic proximity Read ↗

Characterization of EGFR family gene aberrations in cholangiocarcinomaSemantic proximity Read ↗

Targeted Therapies in Neoadjuvant Treatment for Gastroesophageal CancerSemantic proximity Read ↗

Expression of the EGF Family in Gastric Cancer: Downregulation of HER4 and Its Activating Ligand NRG4Semantic proximity Read ↗

Larotinib in Patients with Advanced and Previously Treated Esophageal Squamous Cell Carcinoma with Epidermal Growth Factor Receptor Overexpression or Amplification: An Open-Label, Multicenter Phase 1b StudySemantic proximity Read ↗

Dual targeting of HER3 and EGFR in colorectal tumors might overcome anti-EGFR resistance.Semantic proximity Read ↗

Larotinib in patients with advanced and previously treated esophageal squamous cell carcinoma with epidermal growth factor receptor overexpression or amplification: an open-label, multicenter phase 1b study.Semantic proximity Read ↗

HER-3 Expression and MEK Activation in Non-small Cell Lung CancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.