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Article

Reduced expression of NLRP3 and MEFV in human ischemic heart tissue.

Biochemical and biophysical research communications - 4 Jan 2013

Hermansson Cecilia, Lundqvist Annika, Wasslavik Carina, Palmqvist Lars, Jeppsson Anders, Hultén Lillemor Mattsson

Abstract excerpt

The innate immune system and, in particular, activation of the multi-protein complex known as the inflammasome complex are involved in ischemic injury in myocardial cells. The nucleotide-binding leucine-rich repeat-containing pyrin receptor 3 (NLRP3) inflammasome has been linked to inflammation and NLRP3 is especially important for increased inflammation in atherosclerosis, which may lead to myocardial...

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Source

Identifiers

PMID: 23206693
DOI: 10.1016/j.bbrc.2012.11.070

Genes

NLRP3
MEFV

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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