Article

Association of Inflammasome Gene Expression Levels with Pathogenesis of Familial Mediterranean Fever in Armenians

2024-10-03

Abstract excerpt

Familial Mediterranean fever (FMF) is a genetically determined autoinflammatory disease transmitted by an autosomal recessive mechanism. The cause of the nosology is point mutations of the MEFV (Mediterranean FeVer) gene coding for pyrin protein. Inflammasomes are molecular platforms altered in autoinflammatory diseases. The aim of this study was to evaluate the expression of inflammasome genes (p65, Casp-1, MEFV-...

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Literature Corpus work: bbbc1b04-7aa9-566c-98a8-c55302cd8b60
DOI: 10.20944/preprints202410.0130.v1

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