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Article

Emerging Roles of Inflammasomes in Cardiovascular Diseases

7 Apr 2022

Abstract excerpt

Cardiovascular diseases are known as the leading cause of morbidity and mortality worldwide. As an innate immune signaling complex, inflammasomes can be activated by various cardiovascular risk factors and regulate the activation of caspase-1 and the production and secretion of proinflammatory cytokines such as IL-1β and IL-18. Accumulating evidence supports that inflammasomes play a pivotal role in the...

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PMID: 35464402
DOI: 10.3389/fimmu.2022.834289

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