Antibiotic resistance and stress in the light of Fisher's model.

doi:10.1111/j.1558-5646.2012.01722.x

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Article

Antibiotic resistance and stress in the light of Fisher's model.

Evolution; international journal of organic evolution - 1 Dec 2012

Trindade Sandra, Sousa Ana, Gordo Isabel

Abstract excerpt

The role of mutations in evolution depends upon the distribution of their effects on fitness. This distribution is likely to depend on the environment. Indeed genotype-by-environment interactions are key for the process of local adaptation and ecological specialization. An important trait in bact...

Topics

Biological Evolution
Drug Resistance, Bacterial
Environment
Escherichia coli
Genotype
Mutation
Selection, Genetic
Stress, Physiological

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