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Article

Predictable properties of fitness landscapes induced by adaptational tradeoffs.

eLife - 19 May 2020

Das Suman G, Direito Susana Ol, Waclaw Bartlomiej, Allen Rosalind J, Krug Joachim

Abstract excerpt

Fitness effects of mutations depend on environmental parameters. For example, mutations that increase fitness of bacteria at high antibiotic concentration often decrease fitness in the absence of antibiotic, exemplifying a tradeoff between adaptation to environmental extremes. We develop a mathematical model for fitness landscapes generated by such tradeoffs, based on experiments that determine the antibiotic...

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Identifiers

PMID: 32423531
DOI: 10.7554/eLife.55155
PMCID: PMC7297540

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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