Article
Diabetes and Familial Hypercholesterolemia: Interplay between Lipid and Glucose Metabolism.
Nutrients - 3 Apr 2022
González-Lleó Ana M, Sánchez-Hernández Rosa María, Boronat Mauro, Wägner Ana M
Abstract excerpt
Familial hypercholesterolemia (FH) is a genetic disease characterized by high low-density lipoprotein (LDL) cholesterol (LDL-c) concentrations that increase cardiovascular risk and cause premature death. The most frequent cause of the disease is a mutation in the LDL receptor (LDLR) gene. Diabetes is also associated with an increased risk of cardiovascular disease and mortality. People with FH seem to be...
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