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Article

Mirror-symmetric microtubule assembly and cell interactions drive lumen formation in the zebrafish neural rod.

The EMBO journal - 9 Jan 2013

Buckley Clare E, Ren Xiaoyun, Ward Laura C, Girdler Gemma C, Araya Claudio, Green Mary J, Clark Brian S, Link Brian A, Clarke Jonathan D W

Abstract excerpt

By analysing the cellular and subcellular events that occur in the centre of the developing zebrafish neural rod, we have uncovered a novel mechanism of cell polarisation during lumen formation. Cells from each side of the neural rod interdigitate across the tissue midline. This is necessary for localisation of apical junctional proteins to the region where cells intersect the tissue midline. Cells assemble a...

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Identifiers

PMID: 23202854
DOI: 10.1038/emboj.2012.305
PMCID: PMC3545300

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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