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Article

Genome-wide association studies of coronary artery disease and heart failure: where are we going?

Pharmacogenomics - 1 Feb 2009

Dorn Gerald W, Cresci Sharon

Abstract excerpt

The heart diseases that account for a large amount of morbidity and mortality in the developed world (coronary artery disease, myocardial infarction and heart failure) are phenotypically heterogeneous disorders. It has been suspected for many years that genetics may have an important role in these diseases and their poor outcome. However, their complex and likely polygenic pathophysiology has confounded clear...

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Identifiers

PMID: 19207022
DOI: 10.2217/14622416.10.2.213
PMCID: PMC3428120

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