Article
Identifying functional noncoding variants from genome-wide association studies for cardiovascular disease and related traits.
Current opinion in lipidology - 1 Apr 2015
Smith Andrew J P, Humphries Steve E, Talmud Philippa J
Abstract excerpt
PURPOSE OF REVIEW: Genome-wide association studies have identified many novel loci for cardiovascular disease and related traits. Attention is now shifting towards the analysis of these loci for causal variants, with a view to identify the novel mechanisms leading to disease. RECENT FINDINGS: This review focuses on the approaches to identify causal, noncoding variants for coronary artery disease, lipid traits and...
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