Article
Advances and Challenges for GWAS Analysis in Cardiac Diseases: A Focus on Coronary Artery Disease (CAD).
Current problems in cardiology - 1 Sept 2023
Khan Shahid Ullah, Saeed Sumbul, Alsuhaibani Amnah Mohammed, Fatima Sumaya, Ur Rehman Khalil, Zaman Umber, Ullah Muneeb, Refat Moamen S, Lu Kun
Abstract excerpt
The achievement of genome-wide association studies (GWAS) has rapidly progressed our understanding of the etiology of coronary artery disease (CAD). It unlocks new strategies to strengthen the stalling of CAD drug development. In this review, we highlighted the recent drawbacks, mainly pointing out those involved in identifying causal genes and interpreting the connections between disease pathology and risk...
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