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Article

Pathogenic cellular phenotypes are germline transmissible in a transgenic primate model of Huntington's disease.

Stem cells and development - 15 Apr 2013

Putkhao Kittiphong, Kocerha Jannet, Cho In-Ki, Yang Jinjing, Parnpai Rangsun, Chan Anthony W S

Abstract excerpt

A transgenic primate model for Huntington's Disease (HD) first reported by our group that (HD monkeys) carry the mutant Huntingtin (HTT) gene with expanded polyglutamine (CAG) repeats and, develop chorea, dystonia, and other involuntary motor deficiencies similar to HD [ 1 ]. More recently, we have found that longitudinal magnetic resonance imaging of the HD monkey brain revealed significant atrophy in regions...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23190281
DOI: 10.1089/scd.2012.0469
PMCID: PMC3613972

Genes

HTT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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