Article
Monkey hybrid stem cells develop cellular features of Huntington's disease.
BMC cell biology - 5 Feb 2010
Laowtammathron Chuti, Cheng Eric Ch, Cheng Pei-Hsun, Snyder Brooke R, Yang Shang-Hsun, Johnson Zach, Lorthongpanich Chanchao, Kuo Hung-Chih, Parnpai Rangsun, Chan Anthony W S
Abstract excerpt
BACKGROUND: Pluripotent stem cells that are capable of differentiating into different cell types and develop robust hallmark cellular features are useful tools for clarifying the impact of developmental events on neurodegenerative diseases such as Huntington's disease. Additionally, a Huntington's cell model that develops robust pathological features of Huntington's disease would be valuable for drug discovery...
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