Article
Germline transmission in transgenic Huntington's disease monkeys.
Theriogenology - 15 Jul 2015
Moran Sean, Chi Tim, Prucha Melinda S, Ahn Kwang Sung, Connor-Stroud Fawn, Jean Sherrie, Gould Kenneth, Chan Anthony W S
Abstract excerpt
Transgenic nonhuman primate models are an increasingly popular model for neurologic and neurodegenerative disease because their brain functions and neural anatomies closely resemble those of humans. Transgenic Huntington's disease monkeys (HD monkeys) developed clinical features similar to those seen in HD patients, making the monkeys suitable for a preclinical study of HD. However, until HD monkey colonies can...
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