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Article

Reprogramming Huntington monkey skin cells into pluripotent stem cells.

Cellular reprogramming - 1 Oct 2010

Chan Anthony W S, Cheng Pei-Hsun, Neumann Adam, Yang Jin-Jing

Abstract excerpt

Induced pluripotent Huntington's disease monkey stem cells (rHD-iPSCs) were established by the overexpression of rhesus macaque transcription factors (Oct4, Sox2, and Klf4) in transgenic Huntington's monkey skin fibroblasts. The rHD-iPSCs were pluripotent and capable of differentiating into neuronal cell types in vitro and developed teratoma in immune compromised mice. We also demonstrated the upregulation of...

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Identifiers

PMID: 20936902
DOI: 10.1089/cell.2010.0019
PMCID: PMC2993046

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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