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Article

Joint effect of genetic and lifestyle risk factors on type 2 diabetes risk among Chinese men and women.

PloS one - 1 Jan 2012

Villegas Raquel, Delahanty Ryan, Gao Yu-Tang, Long Jirong, Williams Scott M, Xiang Yong-Bing, Cai Hui, Li Hong-Lan, Hu Frank, Cai Qiuyin, Zheng Wei, Shu Xiao-Ou

Abstract excerpt

More than 40 genetic susceptibility loci have been reported for type 2 diabetes (T2D). Recently, the combined effect of genetic variants has been investigated by calculating a genetic risk score. We evaluated 36 genome-wide association study (GWAS) identified SNPs in 2,679 T2D cases and 3322 controls in middle-age Han Chinese. Fourteen SNPs were significantly associated with T2D in analysis adjusted for age, sex...

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Identifiers

PMID: 23185337
DOI: 10.1371/journal.pone.0049464
PMCID: PMC3504028

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