Article
Assessing the clinical utility of a genetic risk score constructed using 49 susceptibility alleles for type 2 diabetes in a Japanese population.
The Journal of clinical endocrinology and metabolism - 1 Oct 2013
Imamura Minako, Shigemizu Daichi, Tsunoda Tatsuhiko, Iwata Minoru, Maegawa Hiroshi, Watada Hirotaka, Hirose Hiroshi, Tanaka Yasushi, Tobe Kazuyuki, Kaku Kohei, Kashiwagi Atsunori, Kawamori Ryuzo, Maeda Shiro
Abstract excerpt
CONTEXT: Genome-wide association studies (GWASs) have identified over 60 susceptibility loci for type 2 diabetes (T2D). Although the ability of previous genetic information (∼40 loci) to discriminate between susceptible and nonsusceptible individuals is limited, the added benefit of updated genetic information has not been evaluated. OBJECTIVE: We assessed the clinical utility of GWAS-derived T2D susceptibility...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.