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Article

Prognostic implications of the IDH1 synonymous SNP rs11554137 in pediatric and adult AML: a report from the Children's Oncology Group and SWOG.

Blood - 27 Oct 2011

Ho Phoenix A, Kopecky Kenneth J, Alonzo Todd A, Gerbing Robert B, Miller Kristen L, Kuhn Julia, Zeng Rong, Ries Rhonda E, Raimondi Susana C, Hirsch Betsy A, Oehler Vivian, Hurwitz Craig A, Franklin Janet L, Gamis Alan S, Petersdorf Stephen H, Anderson Jeanne E, Godwin John E, Reaman Gregory H, Willman Cheryl L, Bernstein Irwin D, Radich Jerald P, Appelbaum Frederick R, Stirewalt Derek L, Meshinchi Soheil

Abstract excerpt

IDH1 SNP rs11554137 was recently reported in association with poor prognosis in normal karyotype adult acute myeloid leukemia (AML). We aimed to determine the prevalence, clinical associations, and prognostic significance of SNP rs11554137 in unselected pediatric and adult AML patients. Diagnosti...

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Source

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Identifiers

PMID: 21873548
DOI: 10.1182/blood-2011-04-348888
PMCID: PMC3208275

Genes

FLT3
IDH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21873548-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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