Article
Prognostic significance of IDH mutation in adult low-grade gliomas: a meta-analysis.
Journal of neuro-oncology - 1 Jun 2013
Sun Hairui, Yin Lianhu, Li Showwei, Han Song, Song Guangrong, Liu Ning, Yan Changxiang
Abstract excerpt
Mutations in the gene encoding isocitrate dehydrogenase (IDH) have been identified in approximately 65-90 % of low-grade gliomas (LGGs). Various studies examining the relationship between IDH mutation with the clinical outcome in patients with LGGs have yielded inconclusive results. The purpose of the present meta-analysis of literature is to determine this effect. We conducted a meta-analysis of 10 studies (937...
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