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Article

Kinetic competition between RNA Polymerase II and Sen1-dependent transcription termination.

Molecular cell - 10 Jan 2013

Hazelbaker Dane Z, Marquardt Sebastian, Wlotzka Wiebke, Buratowski Stephen

Abstract excerpt

The essential helicase-like protein Sen1 mediates termination of RNA Polymerase II (Pol II) transcription at snoRNAs and other noncoding RNAs in yeast. A mutation in the Pol II subunit Rpb1 that increases the elongation rate increases read-through transcription at Sen1-mediated terminators. Termination and growth defects in sen1 mutant cells are partially suppressed by a slowly transcribing Pol II mutant and are...

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Identifiers

PMID: 23177741
DOI: 10.1016/j.molcel.2012.10.014
PMCID: PMC3545030

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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