Article
Genome-wide distribution of yeast RNA polymerase II and its control by Sen1 helicase.
Molecular cell - 8 Dec 2006
Steinmetz Eric J, Warren Christopher L, Kuehner Jason N, Panbehi Bahman, Ansari Aseem Z, Brow David A
Abstract excerpt
Functional engagement of RNA polymerase II (Pol II) with eukaryotic chromosomes is a fundamental and highly regulated biological process. Here we present a high-resolution map of Pol II occupancy across the entire yeast genome. We compared a wild-type strain with a strain bearing a substitution in the Sen1 helicase, which is a Pol II termination factor for noncoding RNA genes. The wild-type pattern of Pol II...
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