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Article

Testing allele homogeneity: the problem of nested hypotheses.

BMC genetics - 23 Nov 2012

Izbicki Rafael, Fossaluza Victor, Hounie Ana Gabriela, Nakano Eduardo Yoshio, de Bragança Pereira Carlos Alberto

Abstract excerpt

BACKGROUND: The evaluation of associations between genotypes and diseases in a case-control framework plays an important role in genetic epidemiology. This paper focuses on the evaluation of the homogeneity of both genotypic and allelic frequencies. The traditional test that is used to check allelic homogeneity is known to be valid only under Hardy-Weinberg equilibrium, a property that may not hold in practice....

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Identifiers

PMID: 23176636
DOI: 10.1186/1471-2156-13-103
PMCID: PMC3770452

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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