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Article

Reduced TOR signaling sustains hyphal development in Candida albicans by lowering Hog1 basal activity.

Molecular biology of the cell - 1 Feb 2013

Su Chang, Lu Yang, Liu Haoping

Abstract excerpt

Candida albicans is able to undergo reversible morphological changes between yeast and hyphal forms in response to environmental cues. This morphological plasticity is essential for its pathogenesis. Hyphal development requires two temporally linked changes in promoter chromatin, which is sequentially regulated by temporarily clearing the transcription inhibitor Nrg1 upon activation of cAMP/protein kinase A and...

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Identifiers

PMID: 23171549
DOI: 10.1091/mbc.E12-06-0477
PMCID: PMC3564525

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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