Article
Functional characterization of Aspergillus nidulans ypkA, a homologue of the mammalian kinase SGK.
PloS one - 1 Jan 2013
Colabardini Ana Cristina, Brown Neil Andrew, Savoldi Marcela, Goldman Maria Helena S, Goldman Gustavo Henrique
Abstract excerpt
The serum- and glucocorticoid-regulated protein kinase (SGK) is an AGC kinase involved in signal cascades regulated by glucocorticoid hormones and serum in mammals. The Saccharomyces cerevisiae ypk1 and ypk2 genes were identified as SGK homologues and Ypk1 was shown to regulate the balance of sphingolipids between the inner and outer plasma membrane. This investigation characterized the Aspergillus nidulans YPK1...
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