Article
The protein kinase Tor1 regulates adhesin gene expression in Candida albicans.
PLoS pathogens - 1 Feb 2009
Bastidas Robert J, Heitman Joseph, Cardenas Maria E
Abstract excerpt
Eukaryotic cell growth is coordinated in response to nutrient availability, growth factors, and environmental stimuli, enabling cell-cell interactions that promote survival. The rapamycin-sensitive Tor1 protein kinase, which is conserved from yeasts to humans, participates in a signaling pathway central to cellular nutrient responses. To gain insight into Tor-mediated processes in human fungal pathogens, we have...
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