Article
Murine double minute 2 promoter SNP309 polymorphism and prostate cancer risk: a meta-analysis.
International journal of urology : official journal of the Japanese Urological Association - 1 Oct 2012
Liu Guoyuan, Jiang Deke, Shen Suqin, Yu Long
Abstract excerpt
OBJECTIVE: The murine double minute 2 gene encodes a negative regulator of the tumor protein p53. A single nucleotide polymorphism in murine double minute 2 promoter, SNP309 T>G, has been reported to alter murine double minute 2 protein expression and to accelerate tumor formation in humans. We carried out a meta-analysis to explore the association between this polymorphism and prostate cancer risk. METHODS: All...
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