Article
Mammalian epigenomics: reprogramming the genome for development and therapy.
Theriogenology - 1 Jan 2003
Reik W, Santos F, Dean W
Abstract excerpt
Epigenetic modifications of DNA and chromatin are important for genome function during development and in adults. DNA and chromatin modifications have central importance for genomic imprinting and other aspects of epigenetic control of gene expression. In somatic lineages, modifications are generally stably maintained and are characteristic of different specialized tissues. The mammalian genome undergoes major...
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