Article

Epigenetic reprogramming in mammalian nuclear transfer

2004-01-01

Abstract excerpt

Somatic cloning has been succeeded in some species,but the cloning efficiency is very low,which limits the application of the technique in many areas of research and biotechnology.The cloning of mammals by somatic cell nuclear transfer(NT)requires epigenetic reprogramming of the differentiated state of donor cell to a totipotent,embryonic ground state. Accumulating evidence indicates that incomplete or inappropria...

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Literature Corpus work: b3867ad6-e376-50fb-aa1d-9ac9846293fe
DOI: 10.1007/bf02889744

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