Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

How to Improve the Success Rate of Mouse Cloning Technology

1 Jan 2010

Abstract excerpt

It has now been 13 years since the first cloned mammal Dolly the sheep was generated from somatic cells using nuclear transfer (SCNT). Since then, this technique has been considered an important tool not only for animal reproduction but also for regenerative medicine. However, the success rate is still very low and the mechanisms involved in genomic reprogramming are not yet clear. Moreover, the NT technique...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animal Genetics and Reproduction
Share to Pluripotent Stem Cells Research
Share to Reproductive Biology and Fertility

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20203432
DOI: 10.1262/jrd.09-221a

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 17 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

How to Improve the Success Rate of Mouse Cloning TechnologyPMID 20203432Read ↗

Production of Cloned Mice and ES Cells from Adult Somatic Cells by Nuclear Transfer: How to Improve Cloning Efficiency?Semantic proximity Read ↗

Strategies to Improve the Efficiency of Somatic Cell Nuclear TransferSemantic proximity Read ↗

Epigenetic manipulation to improve mouse SCNT embryonic developmentSemantic proximity Read ↗

Epigenetic Reprogramming During Somatic Cell Nuclear Transfer: Recent Progress and Future DirectionsSemantic proximity Read ↗

Lessons Learned from Somatic Cell Nuclear TransferSemantic proximity Read ↗

Advance in the Role of Epigenetic Reprogramming in Somatic Cell Nuclear Transfer-Mediated Embryonic DevelopmentSemantic proximity Read ↗

The many problems of somatic cell nuclear transfer in reproductive cloning of mammalsSemantic proximity Read ↗

Cloned mice and embryonic stem cell establishment from adult somatic cells.Semantic proximity Read ↗

Cloning animals by somatic cell nuclear transfer – biological factorsSemantic proximity Read ↗

Cloning in action: can embryo splitting, induced pluripotency and somatic cell nuclear transfer contribute to endangered species conservation?Semantic proximity Read ↗

Equivalency of Nuclear Transfer‐Derived Embryonic Stem Cells to Those Derived from Fertilized Mouse BlastocystsSemantic proximity Read ↗

Recent advancements in cloning by somatic cell nuclear transferSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.