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Reshaping the transcriptional frontier: Epigenetics and somatic cell nuclear transfer

24 Oct 2013

Abstract excerpt

Somatic-cell nuclear transfer (SCNT) experiments have paved the way to the field of cellular reprogramming. The demonstrated ability to clone over 20 different species to date has proven that the technology is robust but very inefficient, and is prone to developmental anomalies. Yet, the offspring from cloned animals exhibit none of the abnormalities of their parents, suggesting the low efficiency and high...

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PMID: 24167064
DOI: 10.1002/mrd.22271

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