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Article

Resistance studies of a dithiazol analogue, DBPR110, as a potential hepatitis C virus NS5A inhibitor in replicon systems.

Antimicrobial agents and chemotherapy - 1 Feb 2013

Lin Hui-Mei, Wang Jing-Chyi, Hu Han-Shu, Wu Pei-Shan, Wang Wen-Hung, Wu Su-Ying, Yang Chi-Chen, Yeh Teng-Kuang, Hsu Tsu-An, Jiaang Weir-Torn, Chao Yu-Sheng, Chern Jyh-Haur, Yueh Andrew

Abstract excerpt

Hepatitis C virus (HCV), a member of the Flaviviridae family, affects approximately 3% of the world's population and is becoming the leading cause of liver disease in the world. Therefore, the development of novel or more effective treatment strategies to treat chronic HCV infection is urgently needed. In our previous study, we identified a potential HCV NS5A inhibitor, BP008. After further systemic optimization,...

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Share to Drug Resistance, Viral
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Interferon-alpha

Share to Pyrrolidines

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Share to Sequence Analysis, RNA

Share to Thiazoles

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Source

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Identifiers

PMID: 23165461
DOI: 10.1128/AAC.01403-12
PMCID: PMC3553732

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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