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Article

Targeting NS5B RNA-dependent RNA polymerase for anti-HCV chemotherapy.

Current drug targets. Infectious disorders - 1 Sept 2003

Wu Jim Zhen, Hong Zhi

Abstract excerpt

The global prevalence of persistent hepatitis C virus (HCV) infection and the lack of a highly effective and well-tolerated antiviral therapy have spurred intensive efforts to discover and develop novel anti-HCV therapy in the pharmaceutical industry. HCV NS5B RNA-dependent RNA polymerase (RdRp), the centerpiece for viral replication, constitutes a valid target for drug discovery. Compared to the host RNA and DNA...

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Identifiers

PMID: 14529354
DOI: 10.2174/1568005033481114

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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