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Article

Oligomeric structure of 14-3-3 protein: what do we know about monomers?

FEBS letters - 14 Dec 2012

Sluchanko Nikolai N, Gusev Nikolai B

Abstract excerpt

14-3-3s predominantly form homo-/heterodimers that are in equilibrium with corresponding monomers. Dimer/monomer equilibrium depends on the nature and phosphorylation of Ser58 of certain 14-3-3 isoforms. The structure and properties of 14-3-3 dimers are well characterized, whereas 14-3-3 monomers are less investigated. Therefore design and analysis of dimer-incapable mutants of 14-3-3 are important. Truncated or...

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Source

Identifiers

PMID: 23159940
DOI: 10.1016/j.febslet.2012.10.048

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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