Article
Structural basis of 14-3-3 protein functions.
Seminars in cell & developmental biology - 1 Sept 2011
Obsil Tomas, Obsilova Veronika
Abstract excerpt
The 14-3-3 proteins, a family of conserved regulatory molecules, participate in a wide range of cellular processes through binding interactions with hundreds of structurally and functionally diverse proteins. Several distinct mechanisms of the 14-3-3 protein function were described, including conformational modulation of the bound protein, masking of its sequence-specific or structural features, and scaffolding...
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