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Article

A structural basis for 14-3-3sigma functional specificity.

The Journal of biological chemistry - 13 May 2005

Wilker Erik W, Grant Robert A, Artim Stephen C, Yaffe Michael B

Abstract excerpt

The 14-3-3 family of proteins includes seven isotypes in mammalian cells that play numerous diverse roles in intracellular signaling. Most 14-3-3 proteins form homodimers and mixed heterodimers between different isotypes, with overlapping roles in ligand binding. In contrast, one mammalian isofor...

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PMID: 15731107
DOI: 10.1074/jbc.M500982200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15731107-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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