Article
[Relationship between genetic polymorphism of multidrug resistance 1 gene and the risk of childhood acute lymphocytic leukemia].
Zhonghua er ke za zhi = Chinese journal of pediatrics - 1 Sept 2012
Lü Hui, Du Zhi-Zhuo, Wang Wei, Wang Wei, Zhao Wen-li, Wang Yi, Hu Shao-yan, Chai Yi-huan
Abstract excerpt
OBJECTIVE: To investigate the relationship between genetic polymorphism in exon 12 C1236T, exon 21 G2677T/A and exon 26 C3435T of the multidrug resistance 1 (MDR1) gene and the risk of childhood acute lymphocytic leukemia (ALL). METHOD: A total of 176 patients with ALL and a cohort of 170 matched healthy subjects were included. SNaPshot SNP typing was used to determine the genotypes of MDR1 C1236T, G2677T/A,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
