Article
DPYD gene polymorphisms are associated with risk and chemotherapy prognosis in pediatric patients with acute lymphoblastic leukemia.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Aug 2016
Zhao Xiao-Qiang, Cao Wei-Jie, Yang Hai-Ping, Yang Xue-Wen, Tang Ping, Sun Ling, Gao Xing
Abstract excerpt
We aimed to investigate the association between dihydropyrimidine dehydrogenase (DPYD) gene polymorphisms and the risk of pediatric acute lymphoblastic leukemia (ALL) and its prognosis after chemotherapy. A total of 147 pediatric ALL patients diagnosed by our hospital between January 2011 and December 2014 were included in the case group, and 102 healthy people who received a physical examination during the same...
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