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Gene polymorphisms of ABC transporters are associated with clinical outcomes in children with acute lymphoblastic leukemia

1 Jan 2012

Abstract excerpt

INTRODUCTION: Genetic variability affects clinical outcome in pediatric acute lymphocytic leukemia (ALL) patients. Evaluating gene polymorphisms in ABC transporters could help identify relapse risk and predict outcome. MATERIAL AND METHODS: The SNaPshot SNP technique was used to analyze single-nucleotide polymorphisms (SNPs) in the multidrug transporter 1 (MDR1), multidrug resistance associated proteins (MRP1,...

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PMID: 23056078
DOI: 10.5114/aoms.2012.30290

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