Article
Regulatory polymorphisms of multidrug resistance 1 (MDR1) gene are associated with the development of childhood acute lymphoblastic leukemia.
Leukemia research - 1 Dec 2007
Hattori Hiroyoshi, Suminoe Aiko, Wada Morimasa, Koga Yuhki, Kohno Kimitoshi, Okamura Jun, Hara Toshiro, Matsuzaki Akinobu
Abstract excerpt
The aim of this study is to determine whether the polymorphisms of the MDR1 gene are associated with the development of childhood acute lymphoblastic leukemia (ALL). The MDR1 gene polymorphisms, -2352 G>A, -934A>G, -692T>C (5' regulatory region) and 3435C>T (exon 26), were examined in 157 ALL pat...
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