SLCO2B1 c.935G>A single nucleotide polymorphism has no effect on the pharmacokinetics of montelukast and aliskiren.

doi:10.1097/FPC.0b013e32835bac90

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Article

SLCO2B1 c.935G>A single nucleotide polymorphism has no effect on the pharmacokinetics of montelukast and aliskiren.

Pharmacogenetics and genomics - 1 Jan 2013

Tapaninen Tuija, Karonen Tiina, Backman Janne T, Neuvonen Pertti J, Niemi Mikko

Abstract excerpt

OBJECTIVE: A nonsynonymous single nucleotide polymorphism (SNP) in the SLCO2B1 gene encoding organic anion transporting polypeptide 2B1 (OATP2B1), c.935G>A (p.R312Q; rs12422149), has been associated with reduced plasma concentrations of montelukast in patients with asthma. Our aim was to examine the possible effects of the SLCO2B1 c.935G>A SNP on the single-dose pharmacokinetics of the suggested OATP2B1...

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PMID: 23151832
DOI: 10.1097/FPC.0b013e32835bac90

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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