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Article

A systematic review of single nucleotide polymorphisms affecting allopurinol pharmacokinetics and serum uric acid level.

Pharmacogenomics - 1 Jan 2024

A Zairol Azwan Farah Aida, Teo Yi Ying, Mohd Tahir Nor Asyikin, Saffian Shamin Mohd, Makmor-Bakry Mohd, Mohamed Said Mohd Shahrir

Abstract excerpt

Aim: To summarize the effects of single nucleotide polymorphisms (SNPs) on the pharmacokinetics of allopurinol to control uric acid levels.Methods: A comprehensive search was conducted in PubMed, Web of Science and Scopus databases from inception to January 2024, includes 17 articles focusing on SNPs and pharmacokinetics of allopurinol and oxypurinol.Results: A total of 11 SNPs showed a significant association...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39347581
DOI: 10.1080/14622416.2024.2403969
PMCID: PMC11492661

Genes

GREM2
ABCG2
AOX1
PDZK1
SLC17A1
SLC22A12
SLC22A13
SLC2A9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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