Article
Association of glucocorticoid receptor gene NR3C1 genetic variants with angiographically documented coronary artery disease and its risk factors.
Archives of medical research - 1 Jan 2013
Gorący Iwona, Gorący Jarosław, Safranow Krzysztof, Skonieczna-Żydecka Karolina, Ciechanowicz Andrzej
Abstract excerpt
BACKGROUND AND AIMS: Glucocorticoids and their receptors are involved in inflammation and many cardiovascular risk factors. We examined associations of Tth111I, N363S and ER22/23EK NR3C1 gene polymorphisms and haplotypes, with coronary artery disease (CAD), severity of CAD (single-vessel vs. multivessel disease) and risk factors. METHODS: Three hundred ten individuals were submitted to coronary angiography....
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