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Article

MYH rs3219476 and rs3219472 polymorphisms and risk of cholangiocarcinoma.

Molecular medicine reports - 1 Jan 2013

You Si-Hong, Wang Xiang, Huang Shu, Wang Min, Ji Guo-Zhong, Xia Jin-Rong, Fan Zhi-Ning

Abstract excerpt

Cholangiocarcinoma (CCA) is a rare but devastating malignancy. Up to 90% of patients presenting with CCA have no identifiable risk factors. The base excision repair (BER) pathway has a principal role in the repair of mutations caused by oxidized or reduced bases. The MutY homolog (MUTYH, MYH) is one of the key proteins in the BER pathway, but the role of MYH in the tumorigenesis of CCA is largely unknown. In this...

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Source

Identifiers

PMID: 23138270
DOI: 10.3892/mmr.2012.1175

Genes

MUTYH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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